Abstract Background CHD5 is a conventional tumour-suppressing gene in many tumours.The aim of this study was to determine whether CHD5 variants contribute to the risk of hepatocellular carcinoma (HCC).Methods Gene variants were identified using next-generation sequencing targeted on referenced mutations followed by TaqMan genotyping in two case-con
Alexandra Enocson, Kate Jolly, Rachel Elizabeth Jordan, David A Fitzmaurice, SM Greenfield, Peymane Adab On behalf of the BLISS research team Institute of Applied Health Research, University of Birmingham, Edgbaston, Birmingham, West Midlands, UK Background: COPD is a leading cause of morbidity and mortality, yet it remains largely underdiagnosed.C
Abstract Background Effective self-management of chronic health conditions is key to avoiding disease escalation and poor health outcomes, but self-management abilities vary.Adequate patient capacity, in terms of abilities and resources, is needed to effectively manage the treatment burden associated with chronic health conditions.The ability to me